Wednesday, January 8, 2014

Cometriq Positive Trial Results for Prostate Cancer Could Send Shares of Exelixis, Inc. (EXEL) Higher

I really like looking for small-cap biotech stocks that have potential for growth. This is a high-risk industry because a lot of these companies rise and fall on the results of the trials. Investing in companies based upon trial information before it’s brought to market could be highly speculative. It could also be highly profitable if timed properly.

There is one company I recently ran across with a “small market drug” that could drastically increase in value during the next couple of years. If the Phase 2 testing for this specific drug it now markets is positive, this could mean a lot more revenue. The name of the company is Exelixis and it currently has one approved drug on the market called Cometriq.

Cometriq treats thyroid cancer that has metastasized to other parts of the body. Exelixis brought the drug to market in the United States in January 2013 and it has generated a paltry $10.7 million in revenue through September. The annual sales estimates are not expected to top $15 million because the size of the market is so small.

Exelixis is hoping to expand that $15 million revenue base to Europe. The European Committee for Medicinal Products for human use has been looking over the drug for marketing in Europe. The company has a partner, Sobi, which it will work with for distribution in Europe. Exelixis’ progress in commercializing Cometriq remains an important factor for investors to watch.

Besides that, the company does not look like an exciting biotech stock. If you watched it through 2013, you may have fallen asleep. While most of the market prospered, this barely scraped a single digit growth rate.

In fact, the stock really hasn’t moved much at all for the last two years. In January 2012, the stock was just over the five dollar mark; had a couple peaks up to seven but came back down again. Since April 2012, the stock has floated up and down between its high now of 6.8 and around 4.5. There have been no significant moves at all because there has been nothing that the company has been working on with a huge revenue potential until now.

Since there were so many better biotech stocks to look at, this company has consistently been under the radar and neglected by most investors.

Starting Phase 2 Trials

Exelixis has initiated its Phase 2 trial for Cabozantinib, a treatment for castration resistant prostate cancer that had metastasized to the bone and not been previously treated with chemotherapy.

This trial will combine the drug with one already being used to treat prostate cancer called abiraterone with prednisone. This trial testing will compare results against the combination of just prednisone and abiraterone together.

The trial will enroll 280 non-chemotherapy CRPC patients in the trial across 50 sites in North America.

Why could 2014 be a significant year for the stock?

Another company you might be familiar with, Johnson and Johnson (NYSE: JNJ), had a CRPC drug “Zytiga” approved and sales in the first nine months of 2013 topped $1.2 billion. I am not comparing Exelixis to Johnson & Johnson, just the marketing opportunity.

If the Phase 2 studies turn out to be successful, there is a high probability we will be watching the company’s shares increase in value.

Dr. Eric Schmidt, a managing director and senior research analyst at Cowen, believes there is a market potential for a later-line prostate cancer drug in excess of $500 million.

Recently, Maxim Group upgraded its outlook on the company from hold to a buy with a price target of $7.50. That price target represents a 20% return from the current share price. Maxim Group must have faith in the ability of Cabozantinib to produce positive trial results of 2014.

I would encourage “growth investors” to watch this company closely next year; it has all the signs of a possible “growth investment.” If you are a “value investor,” this might turn into a good long-term investment if everything works out right.

As I wrote at the beginning of this article, investing in biotech stocks at this stage is very risky and an investor needs to know what they’re doing if they are going to look at a possible investment like this.

About MissionIR 

MissionIR is committed to connecting the investment community with companies that have great potential and a strong dedication to building shareholder value. We know our reputation is based on the integrity of our clients and go to great lengths to ensure the companies represented adhere to sound business practices.

Sign up for “The Mission Report” at www.MissionIR.com


Please see disclaimer on the MissionIR website http://www.missionir.com/disclaimer.html