The International Stem Cell Corporation, a biotechnology
company, continues its developmental research of using stem cells to advance
regenerative medicine. The company uses stem cell technology called
parthenogenesis that uses unfertilized eggs to address immune system rejection.
These eggs have duplicate sets of human leukocyte antigen genes (HLA) that
lessen the chance of immune rejection. A single line of these cells can treat
millions of people. Furthermore, ISCO can draw hpNSC (human parthenogenetic
neural stem cells) from the unfertilized eggs for self-renewing processes
related to degeneration.
For example, after continuous successful testing, ISCO
believes that their hpNSC can replace dead and dying neurons while also
protecting existing ones when transplanted into the brain of someone with
Parkinson’s disease. Likewise, ISCO scientists have taken steps to develop
human retinal epithelium (RPE) cells that can treat many eye diseases like
age-related macular degeneration. Along with that research, the company is
among the first in the world to develop a method (CytoCor) for creating corneal
tissue and cells to treat blindness.
ISCO recently announced its development of technology that
creates functional cartilage from a person’s skin to treat osteoarthritis, a
joint disease that erodes cartilage. The company is also pursuing other
therapeutic systems that “can potentially be treated with the patient’s own
cells,” said its chief scientific officer, Ruslan Semechkin, PhD.
While continuing to develop new regenerative techniques,
ISCO also maintains a cosmeceutical line called Lifeline Skin Care Inc. This
business manufactures cosmetic skin care products around the world. It uses
parthenogenetic stem cells along with vitamins and minerals to create a
rejuvenating serum that promotes healthy skin.
For more information about ISCO, visit www.internationalstemcell.com
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