VistaGen Therapeutics is a
biotechnology company whose focus is on applying pluripotent stem cell technology
for drug rescue and regenerative medicine. The company, which is based out of
San Francisco, has been in the business of human pluripotent stem cell (hPSC)
technology for over 16 years.
Human pluripotent cells are
the building blocks of all cells of the human body. VistaGen believes that
controlling the differentiation of these kinds of cells can make stronger and
better cells that will benefit drug rescue and regenerative medicine
initiatives.
VistaGen’s approach to drug
rescue and regenerative medicine is unique because of the products the company
chooses to work with. It selects drug candidates that have been abandoned by
other biotechnology and pharmaceutical companies and uses its technology to
generate new chemical variants of them.
These candidates are
perfectly usable, but were abandoned before the market approval stage because
of concerns related to their effect on patients’ hearts and livers.
VistaGen is confident it can
rework these abandoned candidates into something usable, with an end goal of
creating a pipeline of Drug Rescue Variants™. These Variants can then be sold
to biotechnology and pharmaceutical companies who can then develop them, get
them approved, and then sell them commercially.
VistaGen shared exciting
news in April 2014 when it found out that it had received a Notice of Allowance
from the United States Patent and Trademark Office regarding an application for
a patent to expand one of its technology platforms, LiverSafe 3D™. The patent
will expand VistaGen’s intellectual property portfolio to stem cell culture
systems that produce cells for the liver, lung, pancreas, and thyroid. The
company believes that LiverSafe 3D™ will benefit from this expanded
intellectual platform.
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