- PBIO’s
proprietary Ultra Shear Technology (UST) platform achieves the long
sought-after ability to create truly water-soluble CBD oil that can
provide optimized bioavailability
- CBD
sales are projected to reach $89 billion by 2024 with a CAGR of 37 percent
(2018-2024 forecast period)
- Analysts
predict that the biggest short-term challenge for CBD businesses will be
oversaturation and stiff competition in the marketplace; companies
producing the highest-quality, most bioavailable CBD products are expected
to earn top customer loyalty
Finding success in the lucrative yet ultra-competitive CBD
industry is a daunting challenge for businesses in the space, with
oversaturation in the marketplace being a real concern. The cannabis market was
valued at $14.5 billion in 2018 and is projected to reach $89.1 billion by
2024, with a compound annual growth rate of 37 percent during the forecast
period, according to Mordor Intelligence (http://ibn.fm/fCnCI). CBD manufacturers may find tapping
into this booming trend to be short-lived if their CBD offerings don’t stand up
to consumers’ expectations that the products they purchase are as beneficial as
advertised.
Pressure BioSciences Inc. (OTCQB: PBIO), a leader in the
development and sale of high pressure-based instruments, consumables and
related services for the global life sciences and other industries, has
developed a novel, proprietary process that has wide potential in the cannabis
sector by solving one of the most critical problems facing CBD manufacturers
today: the extremely poor water solubility of CBD oil. The recent launch of
PBIO’s BaroShear K45 system, based on the company’s proprietary Ultra Shear
Technology (UST) platform, has been optimized for the unique purpose of
creating high quality, water-soluble nanoemulsions of CBD oil in water, as a
news release details (http://ibn.fm/MY4mE).
CBD, a non-psychoactive compound believed to offer powerful
health benefits, is extracted from the cannabis plant in an oil. After
ingestion, because oils are not well absorbed, most of the CBD is flushed from
the body, leaving little of the product to provide its beneficial properties.
Because of these solubility issues, many CBD products on the market today
contain an inefficient over-abundance of CBD and/or undesirable chemicals to
try and improve solubility and bioavailability.
Dr. Nathan Lawrence, senior advisor to Pressure BioSciences,
said that PBIO solves the water-solubility problem of CBD with its patented UST
platform, which uses ultra-high pressure to create extreme shearing forces to
make highly stable, homogenized nanoemulsions of materials that normally do not
mix, such as CBD oil and water.
“The unique concept of the BaroShear K45 system is based on
PBIO’s proprietary UST platform. It was designed for the efficient and
affordable manufacture of limited quantity oil-based material into high quality,
water-soluble nanoemulsions,” Dr. Lawrence stated in a news release. “The
BaroShear K45 system uses a custom-designed, highly responsive ultra-high
pressure generating subsystem, matched to our patented BaroIsolator device and
NanoGap valve. This allows for the highest effectiveness possible at working
pressures up to 45,000 psi. The BaroShear K45 system is ideally suited for
processing small amounts (e.g., 50 mL – 2 L) of high value product, such as CBD
oil, into water-soluble nanoemulsions with high yield.”
In a critical review report on cannabidiol (CBD), the World
Health Organization’s Expert Committee on Drug Dependence noted that, while CBD
is seen as a useful treatment for a number of medical conditions, there are
efficacy issues because of its “poor aqueous solubility.”
“The absorption of CBD from the gastrointestinal tract is
erratic, and the resulting pharmacokinetic profile is variable. Bioavailability
from oral delivery was estimated to be 6 percent due to significant first-pass
metabolism,” the report states (http://ibn.fm/k9TiL).
For most oil-based products, the ability to prepare them as
nanoemulsions can improve the product’s absorption, medicinal benefits, visual
appearance and sensory presentation. The biggest challenge in the short-term
for CBD businesses will be oversaturation and stiff competition, a Forbes
article notes (http://ibn.fm/rq67C).
As consumers start to learn more about CBD and approach products with more
discerning tastes, companies will need to start differentiating themselves from
their competitors through smart branding and the delivery of excellent
products.
Two short videos released by PBIO (http://ibn.fm/T4eUX and http://ibn.fm/ENM6e), showing
how its patented UST platform was able to process CBD plant oil into a
water-soluble nanoemulsion, give a quick lesson in PBIO’s proprietary
technology. When the UST-processed CBD oil was added to different liquids –
such as a soft drink, a sports drink and a beer – the nanoemulsified CBD oil
completely dissolved in each liquid. For CBD companies seeking a way to stand
out from the rising hordes of competition, PBIO’s BaroShear K45 system could be
a true game changer.
“We are looking forward to working with the early adopters
of this exciting technology platform,” Richard T. Schumacher, president and CEO
of PBIO, said in a news release. “Early adopters will be the first to use the
UST platform in the CBD field, thus giving them a significant head-start over
companies who choose to wait or use other methods.”
For more information, visit the company’s website at www.PressureBioSciences.com
NOTE TO INVESTORS: The latest news and updates
relating to PBIO are available in the company’s newsroom at http://ibn.fm/PBIO
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